In quickly getting old societies like Japan, the straightforward act of swallowing meals will be difficult for a lot of. This situation, generally known as dysphagia, impacts hundreds of thousands of individuals worldwide and may considerably deteriorate an individual’s high quality of life. Whereas texture-modified meals like purées could make swallowing safer, it’s troublesome to tailor these meals to the broad spectrum of dysphagia, as some people can tolerate extra strong meals whereas others require a lot softer textures.
Publishing within the journal Scientific Reviews, analysis groups from Kyushu College and Cardiff College have developed a brand new 3D bioprinting technique that may customise the feel, adhesiveness, and water retention of protein-based emulsion gels for dysphagia diets utilizing managed radiofrequency (RF) and microwave (MW) power.
“For many individuals with dysphagia, meals are sometimes restricted to jelly-like supplies, which might diminish the enjoyment of consuming,” explains Shuntaro Tsubaki, first writer and Affiliate Professor at Kyushu College’s School of Agriculture. “Our objective is to create meals that aren’t solely protected but in addition interesting.”
Tsubaki noticed a chance to use his experience in microwave engineering to unravel this problem. “Typical heating strategies warmth all the things inside indiscriminately—each the components you wish to react and the components you do not,” he elaborates. “Microwaves are completely different. They are often managed to warmth solely particular supplies selectively. This precision is the important thing.”
The crew first developed a bioink that’s composed of two foremost compounds: a steady oil-in-water emulsion and an aqueous resolution containing egg white protein and stabilizers. These are then mixed with a small quantity of magnesium chloride, which acts as a microwave absorption help, serving to the bioink to warmth effectively and selling the protein denaturation crucial for the liquid to solidify right into a gel.
To print this bioink, the crew constructed a customized 3D bioprinter utilizing Lego Mindstorms EV3 impressed by earlier analysis from their Cardiff College collaborators.
“After our preliminary checks proved we might management the gel’s texture with completely different power frequencies, we then loaded the bioink into the 3D printer and extruded it by way of a skinny applicator,” explains Tsubaki.
“Because the bioink passes by way of the applicator, we apply a managed burst of RF or MW power to it, turning the bioink right into a gel. That gel is deposited onto the printing dish layer by layer because the bioprinter nozzle strikes throughout the dish.”

The crew’s experiments demonstrated that by merely altering the frequency of the power utilized, they might produce gels with a variety of properties appropriate for various dysphagia weight-reduction plan necessities.
Once they used a decrease frequency of 200 MHz, which falls within the radiofrequency vary, the ensuing gel was considerably tougher and held its construction and water content material extra successfully. In distinction, utilizing the next frequency of two.45 GHz, just like that of a regular kitchen microwave, produced a gel that was a lot softer and extra adhesive.
“The essential factor is that we will management the feel by frequency, making a custom-made texture for every particular person’s wants,” concludes Tsubaki.
“Our new technique holds potential past dysphagia diets—extending to synthetic meat, useful diet, medical meals, and even area rations. We’re already engaged on different edible supplies that may be 3D bioprinted. The power to manage protein aggregation and even lure flavors contained in the oil section might additionally result in flavor-enhanced food-tech merchandise.”
Extra info:
Shuntaro Tsubaki et al, Radiofrequency and microwave 3D bioprinting of emulsion gel for dysphagia diets, Scientific Reviews (2025). DOI: 10.1038/s41598-025-06804-1
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3D printing technique crafts customizable meals for individuals who have hassle swallowing (2025, August 22)
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